Conservation Calculation
نویسندگان
چکیده
منابع مشابه
AL2CO: calculation of positional conservation in a protein sequence alignment
MOTIVATION Amino acid sequence alignments are widely used in the analysis of protein structure, function and evolutionary relationships. Proteins within a superfamily usually share the same fold and possess related functions. These structural and functional constraints are reflected in the alignment conservation patterns. Positions of functional and/or structural importance tend to be more cons...
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ژورنال
عنوان ژورنال: Science
سال: 2012
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.337.6102.1584-a